Postdoctoral Fellow
Mass General Brigham relies on a wide range of professionals, including doctors, nurses, business people, tech experts, researchers, and systems analysts to advance our mission. As a not-for-profit, we support patient care, research, teaching, and community service, striving to provide exceptional care. We believe that high-performing teams drive groundbreaking medical discoveries and invite all applicants to join us and experience what it means to be part of Mass General Brigham.
Job Summary
SummaryWe are seeking a highly motivated, entry-level postdoctoral fellow with an outstanding record of research productivity and strong potential for an independent academic career. The successful candidate should have demonstrated scientific creativity and the ability to lead research projects, as evidenced by multiple first-author publications in high-quality peer-reviewed journals (or manuscripts currently under review). Working under the mentorship of Dr. Hirotaka Iijima and Dr. Fabrisia Ambrosio, the fellow will conduct independent and collaborative research investigating the molecular, cellular, and systems-level mechanisms underlying musculoskeletal aging, tissue degeneration, and regeneration.
The position offers a unique opportunity to integrate bioengineering, tissue engineering, organ-on-chip technologies, multi-omics, network medicine, computational biology, and in vivo models to address fundamental questions in musculoskeletal biology and regenerative medicine. The fellow will be expected to develop innovative experimental approaches, contribute intellectually to ongoing projects, publish in high-impact journals, compete for fellowship and career development awards, and help mentor junior trainees within a highly collaborative and interdisciplinary research environment.
Essential Functions
- Lead independent research projects investigating the molecular and cellular mechanisms of musculoskeletal aging, joint degeneration, tissue regeneration, and musculoskeletal resilience.
- Design, develop, and optimize advanced bioengineered in vitro platforms, including organ-on-chip systems, 3D tissue-engineered constructs, and physiologically relevant culture models.
- Integrate experimental approaches with multi-omics profiling, systems biology, computational biology, and network medicine to identify mechanisms regulating tissue function and inter-tissue communication.
- Perform molecular and cellular biology experiments, including primary cell isolation and culture, functional assays, gene and protein expression analyses, and advanced imaging.
- Conduct small-animal experiments, including animal handling, intraperitoneal and intra-articular injections, tissue collection, histology, and molecular characterization.
- Design rigorous experiments, analyze and interpret complex datasets, troubleshoot experimental challenges, and maintain accurate research documentation.
- Stay current with emerging technologies and incorporate innovative methodologies into ongoing research.
- Prepare high-quality manuscripts for publication in leading peer-reviewed journals and present findings at national and international scientific meetings.
- Contribute to the preparation of fellowship applications, NIH grants, foundation proposals, and other competitive funding opportunities by generating preliminary data and assisting with grant writing.
- Mentor graduate students, research assistants, and other junior laboratory members while fostering a collaborative and intellectually stimulating research environment.
- Work independently with minimal supervision while actively contributing to interdisciplinary collaborations across engineering, biology, computational science, and clinical research.
Qualifications
Education
Doctorate Related Field of Study required
Can this role accept experience in lieu of a degree?
No
Licenses and Credentials
Experience
Previous Research experience 3-5 years preferred
Knowledge, Skills and Abilities
- Demonstrated experience in research techniques, methods, or research areas relevant to the project.
- Proficient analytical skills, proficiency in statistical software, and excellent written and verbal communication skills.
- Ability to work independently as well as collaboratively within a team.
- Good interpersonal and communication skills.
Additional Job Details (if applicable)
$70,000 - $71,500
Remote Type
Work Location
Scheduled Weekly Hours
Employee Type
Work Shift
EEO Statement:
Mass General Brigham Competency Framework
At Mass General Brigham, our competency framework defines what effective leadership “looks like” by specifying which behaviors are most critical for successful performance at each job level. The framework is comprised of ten competencies (half People-Focused, half Performance-Focused) and are defined by observable and measurable skills and behaviors that contribute to workplace effectiveness and career success. These competencies are used to evaluate performance, make hiring decisions, identify development needs, mobilize employees across our system, and establish a strong talent pipeline.
