How to Apply to Seagen

8 min read Last updated April 20, 2026 14 open positions
Blake Crosley
Blake Crosley Researched using publicly available information, hiring data, and ATS analysis.

Key Takeaways

  • Apply through Pfizer's Workday tenant (pfizer.wd1.myworkdayjobs.com/PfizerCareers), not seagen.com — the legacy career site no longer exists.
  • Filter for 'Bothell' location to target legacy Seagen roles; the Bothell campus is now the operational center of Pfizer Oncology globally.
  • Adcetris, Padcev, Tukysa, and Tivdak are the four commercial brands that define the franchise; speak to them specifically in cover letters and interviews.
  • Expect 4-6 interview rounds with explicit behavioral competency assessment, plus a job talk for most scientific roles.
  • Return-to-office is enforced at three days per week for hybrid roles; lab and manufacturing roles are fully onsite in Bothell.
  • G&A roles (HR, finance, communications, legal) face structural headwinds from ongoing integration; R&D, clinical, biostats, regulatory, and commercial oncology roles continue to grow.
  • Compensation now follows Pfizer's centralized bands — competitive but less negotiable than under pre-acquisition Seagen, with Pfizer RSUs replacing the legacy Seagen equity that was cashed out at $229/share.

About Seagen

Seagen was a Bothell, Washington biotechnology company that pioneered the modern antibody-drug conjugate (ADC) era. Founded in 1997 (originally as Seattle Genetics, rebranded to Seagen in 2020), the company spent more than two decades engineering targeted cancer therapies that link cytotoxic payloads to monoclonal antibodies, sparing healthy tissue and concentrating cellular damage on tumor cells. In December 2023, Pfizer closed its $43 billion acquisition of Seagen — the largest deal in Pfizer's history and the centerpiece of its push to rebuild a leadership position in oncology after losing patent exclusivity on several blockbusters. The Seagen brand is now sunsetting; the Bothell campus operates as Pfizer Oncology Bothell, and the legacy Seagen.com domain 301-redirects to Pfizer.com. Bothell is now the operational headquarters of Pfizer's global oncology business, a deliberate strategic reversal of Pfizer's historical center of gravity in New York City and Cambridge, Massachusetts. Seagen's commercial portfolio defines the modern ADC field. Adcetris (brentuximab vedotin), approved by the FDA in 2011, was the first ADC of the modern era and remains a cornerstone therapy for Hodgkin lymphoma and several T-cell lymphomas, with frontline label expansions throughout the 2010s establishing it as standard of care. Padcev (enfortumab vedotin), partnered with Astellas, became the first-line standard of care for advanced urothelial (bladder) cancer in combination with Merck's Keytruda after a landmark 2024 label expansion and the EV-302 confirmatory readout that displaced platinum-based chemotherapy as the default starting therapy. Tukysa (tucatinib) is a HER2-selective small-molecule tyrosine kinase inhibitor used in HER2-positive metastatic breast cancer, including the difficult-to-treat subgroup with brain metastases where it has demonstrated central-nervous-system activity. Tivdak (tisotumab vedotin), partnered with Genmab, is approved for recurrent or metastatic cervical cancer and represents the first ADC approved in that gynecologic-oncology setting. Pre-acquisition, Seagen employed roughly 3,500 people, the majority concentrated on the Bothell campus north of Seattle, with additional sites in Bay Area research, European clinical operations, and a Canada office. The company was founded by Clay Siegall, who served as CEO for more than two decades before he was forced out in 2022 amid personal allegations; Felix Baker and Baker Bros. Advisors were long-running shareholders and meaningfully influenced strategic direction during the run-up to the Pfizer transaction. Post-acquisition, hiring momentum continues in clinical development, translational medicine, ADC chemistry and manufacturing controls, biostatistics, regulatory affairs, medical affairs, and commercial oncology, while general-and-administrative functions (HR, finance, legal, internal communications, IT) have been reduced through 2024 and 2025 integration-driven layoffs as Pfizer eliminated duplicative corporate roles. The net effect: Bothell is growing in scientific and commercial weight while shrinking in headcount on the corporate side.

Application Process

  1. 1
    Apply through the Pfizer Workday careers portal at pfizer

    Apply through the Pfizer Workday careers portal at pfizer.wd1.myworkdayjobs.com/PfizerCareers — filter by location 'United States - Washington - Bothell' to find legacy Seagen roles. The seagen.com career site no longer exists and redirects to Pfizer.com.

  2. 2
    Create a Pfizer Workday candidate profile carefully on first use; you will reuse

    Create a Pfizer Workday candidate profile carefully on first use; you will reuse this account for every future application. Upload a single PDF resume (avoid Workday's autofill resume parser when possible — it frequently mangles ADC chemistry terminology and clinical trial acronyms).

  3. 3
    Expect an initial recruiter screen within 1-3 weeks for in-demand roles (Bothell

    Expect an initial recruiter screen within 1-3 weeks for in-demand roles (Bothell oncology) and 4-8 weeks for cross-site roles competing with Pfizer's broader hiring queues. Recruiters are now Pfizer Talent Acquisition, not the original Seagen team.

  4. 4
    Hiring managers conduct the first technical conversation, typically 45-60 minute

    Hiring managers conduct the first technical conversation, typically 45-60 minutes via Microsoft Teams. For scientific roles, bring a one-slide summary of your most relevant project and be prepared to discuss it without a deck if asked.

  5. 5
    Plan for a virtual or onsite panel of 4-6 interviews covering technical depth, c

    Plan for a virtual or onsite panel of 4-6 interviews covering technical depth, cross-functional collaboration, and Pfizer's PfizerForward operating principles. Onsite loops at Bothell often include a campus tour and informal conversations with future peers.

  6. 6
    Scientific candidates (R&D, translational, biostats, clinical pharmacology) usua

    Scientific candidates (R&D, translational, biostats, clinical pharmacology) usually present a 30-45 minute job talk on prior published or unpublished work. Industry candidates can present a case study; academics present thesis or postdoc work.

  7. 7
    Reference checks occur after the panel and before any offer

    Reference checks occur after the panel and before any offer. Pfizer uses a third-party background and education verification service; expect to provide degree transcripts and three professional references.

  8. 8
    Offers run through Pfizer's centralized compensation team

    Offers run through Pfizer's centralized compensation team — base, target bonus (typically 15-25% for individual contributors, higher for directors), Pfizer RSUs (legacy Seagen equity already cashed out at $229/share), and Bothell-area relocation if applicable. Negotiation is possible but more constrained than under pre-acquisition Seagen.

Resume Tips for Seagen

recommended

Lead with ADC, oncology, or rare-disease experience if you have it

Lead with ADC, oncology, or rare-disease experience if you have it. Bothell hiring managers prioritize candidates who already understand antibody engineering, linker chemistry, payload selection, bioconjugation, or solid-tumor clinical development.

recommended

Use specific molecule names and mechanisms rather than generic phrases

Use specific molecule names and mechanisms rather than generic phrases. 'Led CMC strategy for vedotin-class ADC' lands better than 'led drug development'. Name MMAE, DM1, DM4, DXd, topoisomerase inhibitors, or your specific payload class.

recommended

Quantify clinical and regulatory deliverables

Quantify clinical and regulatory deliverables. 'Authored Module 2.7.3 supporting sBLA approval; reduced FDA query response time from 14 to 6 days' is the level of specificity Pfizer Oncology screeners reward.

recommended

List therapeutic areas in order of Pfizer relevance: hematologic malignancies (A

List therapeutic areas in order of Pfizer relevance: hematologic malignancies (Adcetris), urothelial and HER2+ solid tumors (Padcev, Tukysa), gynecologic oncology (Tivdak), then broader oncology, then non-oncology. Match the role.

recommended

For non-scientific roles (commercial, finance, HR, legal), emphasize biotech or

For non-scientific roles (commercial, finance, HR, legal), emphasize biotech or pharma transitions, M&A integration experience, or healthcare regulated-environment exposure. Pfizer post-merger especially values people who have lived through Big Pharma integration.

recommended

Keep the resume to 2 pages for ICs, 3 pages maximum for senior directors and VPs

Keep the resume to 2 pages for ICs, 3 pages maximum for senior directors and VPs. Workday's parser handles standard headings (Experience, Education, Publications, Patents) far better than creative formats — avoid two-column layouts.

recommended

Add a short Publications and Patents section if you have peer-reviewed work or f

Add a short Publications and Patents section if you have peer-reviewed work or filed IP. For senior R&D candidates, link to ORCID or Google Scholar in the header. Pfizer hiring committees actually look these up.

recommended

Localize for the Bothell labor market in the cover letter

Localize for the Bothell labor market in the cover letter. Mention specific Pfizer Oncology programs (Padcev EV-302, Tukysa HER2CLIMB-02, ADC pipeline expansion) you would want to contribute to.

ATS System: Workday (Pfizer tenant)

Since the December 2023 acquisition closed, all legacy Seagen roles are posted exclusively through Pfizer's Workday tenant at pfizer.wd1.myworkdayjobs.com/PfizerCareers. The original Seagen Workday tenant has been retired and the seagen.com career site 301 redirects to pfizer.com. Workday at Pfizer is configured with strict parsing rules, mandatory profile fields, and an integrated assessment trigger for select roles.

  • Submit a clean, single-column PDF resume. Workday's resume parser misreads two-column layouts, headers in text boxes, and graphical elements — fields silently arrive blank in the recruiter's view.
  • Filter Bothell roles by selecting 'United States - Washington - Bothell' in the Location facet (or search 'Bothell'). Many ADC roles are also tagged at Cambridge MA, La Jolla CA, or Pearl River NY — apply to the location you can credibly relocate to.
  • Workday will pre-fill education, work history, and skills from your parsed resume. Always review every field — degree dates, employer names, and job titles are the most common parser errors.
  • Pfizer's tenant uses standardized Job Categories (Medical, Research and Development, Commercial, Manufacturing, Quality, Regulatory). Pick the right category in your candidate profile so future Pfizer roles surface in your alerts.
  • Set up Workday job alerts with the 'Bothell' keyword — Pfizer Oncology roles are spread across multiple sites and a saved alert is the only reliable way to catch new postings within 24 hours of go-live.
  • If you applied to Seagen before December 2023, your old candidate profile no longer exists. You must create a new Pfizer Workday account.

Interview Culture

Legacy Seagen culture was famously informal, science-first, and Pacific-Northwest casual — flannel-and-jeans deep technical conversation rather than New York-pharma performative polish.

Walking the Bothell campus pre-acquisition, you would see senior scientists, principal investigators, and executives blending in the same cafeteria, and the dress code defaulted to fleece and trail shoes year-round. Post-acquisition, that Bothell ethos persists in R&D and clinical-development interviews, but it has been layered with Pfizer's more structured competency-based interview framework and a stricter return-to-office mandate (currently three days per week onsite for hybrid roles, with most lab and manufacturing roles fully onsite five days). Interviewers are trained to probe against a defined set of behavioral competencies — Courage, Excellence, Equity, and Joy are the publicly stated Pfizer values — and you should expect at least two STAR-format behavioral questions in every panel session, often using the format 'Tell me about a time you...' followed by Situation, Task, Action, and Result follow-ups. For scientific candidates, the bar remains high: be ready for whiteboard mechanism-of-action questions, study design critiques, and pointed questions about your understanding of ADC linker stability, DAR (drug-to-antibody ratio), bystander effect, internalization kinetics, and resistance mechanisms. Process chemistry, analytical, and CMC candidates should expect technical depth on bioconjugation, payload synthesis, and CGMP. For commercial candidates, expect a case study on launch sequencing, payer access strategy, or competitive positioning against Daiichi Sankyo's Enhertu, AstraZeneca's broader oncology portfolio, or Gilead's Trodelvy. Clinical-operations and regulatory candidates should be ready to discuss specific INDs, IBs, sBLAs, or post-marketing commitments they have personally driven. Across all functions, the interviewers will assess whether you can operate inside a much larger matrixed organization than pre-acquisition Seagen — explicitly demonstrating cross-functional collaboration, comfort with formal governance, and the ability to navigate global teams across time zones is now table stakes.

What Seagen Looks For

  • Deep, demonstrable expertise in your discipline — Pfizer Oncology hires specialists, not generalists, especially in Bothell scientific functions.
  • Direct ADC, targeted therapy, or solid-tumor clinical experience for R&D and clinical development roles, or willingness to learn the modality from a closely adjacent area (CAR-T, bispecifics, radioligand).
  • Comfort with regulated environments — GxP, ICH, FDA and EMA submission experience, audit readiness, and the documentation discipline that Big Pharma requires.
  • Cross-functional collaboration evidence. Pfizer is matrixed; lone-wolf operators, even brilliant ones, struggle. Be able to describe specific cross-team wins.
  • Patient focus expressed concretely. Pfizer interviewers often ask why you want to work in oncology — vague answers fail. Tie your motivation to a specific disease, patient experience, or unmet need.
  • Integration resilience. Many interviewers have lived through 2024-2025 layoffs and reorganizations. Candidates who project stability, judgment, and the ability to operate during organizational change land better than candidates who project only ambition.
  • Willingness to be onsite in Bothell three or more days a week for hybrid roles. Pfizer has tightened RTO since 2024 and remote-first candidates for Bothell-anchored roles are filtered out early.
  • Cultural alignment with Pfizer's stated values — Courage, Excellence, Equity, Joy — referenced naturally rather than recited.

Frequently Asked Questions

Does Seagen still exist as a separate company?
No. Pfizer's $43 billion acquisition of Seagen closed in December 2023, and the Seagen brand is sunsetting. The Bothell, Washington campus continues to operate as Pfizer Oncology Bothell and serves as the operational center of Pfizer's global oncology business. The seagen.com domain now 301 redirects to pfizer.com.
Where do I apply for legacy Seagen jobs?
All openings are posted on Pfizer's Workday careers portal at pfizer.wd1.myworkdayjobs.com/PfizerCareers. Filter the Location facet for 'United States - Washington - Bothell' to surface roles based at the legacy Seagen campus. Many ADC and oncology roles also list secondary locations in Cambridge MA, La Jolla CA, Collegeville PA, and New York NY.
What ATS does Pfizer use for Bothell roles?
Pfizer uses Workday across all global sites including Bothell. The CXS-API-backed tenant lives at pfizer.wd1.myworkdayjobs.com/PfizerCareers. Workday's resume parser is finicky — submit a clean single-column PDF, avoid two-column layouts, and verify every parsed field before submitting your application.
Is Pfizer still hiring at the Bothell campus after the layoffs?
Yes. While 2024 and 2025 reductions hit G&A and corporate functions, Pfizer has explicitly chosen Bothell as the operational center of its global oncology business. R&D, clinical development, biostatistics, regulatory affairs, ADC chemistry and manufacturing, and commercial oncology continue to actively recruit. As of mid-April 2026 the Workday tenant lists active openings in Bothell.
What are the four main Seagen-origin products I should know?
Adcetris (brentuximab vedotin) for Hodgkin lymphoma and T-cell lymphomas — the first modern ADC, FDA-approved in 2011. Padcev (enfortumab vedotin) for advanced urothelial cancer, partnered with Astellas, now first-line standard of care in combination with Keytruda. Tukysa (tucatinib) for HER2-positive metastatic breast cancer including brain metastases. Tivdak (tisotumab vedotin) for recurrent or metastatic cervical cancer, partnered with Genmab.
What is the return-to-office policy?
Pfizer enforces a three-day-per-week onsite mandate for hybrid roles, tightened from a more flexible posture under pre-acquisition Seagen. Lab, manufacturing, and quality roles are fully onsite. If you cannot credibly relocate to or commute to Bothell, you should expect to be screened out of Bothell-anchored postings.
How long does the interview process take?
Plan for 6 to 12 weeks from initial recruiter screen to offer for most professional roles, longer for senior director and VP positions or roles requiring relocation. The process typically includes a recruiter screen, a hiring manager call, a 4-6 person panel (with a job talk for scientific roles), and a final reference and background check phase before offer.
Is the original Seagen culture still intact?
Partially. The Bothell campus retains its science-first, Pacific Northwest casual ethos in R&D and clinical functions, but it now operates inside Pfizer's matrixed structure with formal competency-based interviews, centralized compensation bands, and tighter RTO enforcement. Candidates who can operate inside a Big Pharma matrix while still doing exceptional science do best.
What happened to Seagen equity for current employees?
Legacy Seagen shares were cashed out at $229 per share at deal close in December 2023. Current employees now receive Pfizer RSUs as part of their long-term incentive package, with vesting schedules and performance criteria following Pfizer's standard equity programs.
What backgrounds give the strongest edge for ADC roles?
Direct ADC experience — antibody engineering, linker chemistry, payload selection, bioconjugation, ADC PK/PD, or solid-tumor clinical development with ADCs — is the gold standard. Adjacent modality experience (bispecifics, CAR-T, radioligand therapy, targeted small molecules) is well received. For non-discovery roles, regulatory submission experience for biologics, oncology commercial launch experience, or biotech-to-pharma integration experience are the strongest signals.

Open Positions

Seagen currently has 14 open positions.

Check Your Resume Before Applying → View 14 open positions at Seagen

Related Resources

Similar Companies

Sources

  1. Pfizer Completes Acquisition of Seagen (December 14, 2023) —
  2. Pfizer Careers Portal (Workday tenant) —
  3. Pfizer Oncology overview —
  4. FDA Approval History: Adcetris (brentuximab vedotin) —
  5. Padcev plus Keytruda Approved as First-Line Treatment for Advanced Bladder Cancer (FDA, 2023-2024 label expansions) —
  6. Tukysa (tucatinib) Prescribing Information —
  7. Tivdak (tisotumab vedotin) Accelerated Approval (FDA, 2021) —
  8. Pfizer Announces Cost-Saving Initiatives and Restructuring (2024-2025) —
  9. Seagen Founder Clay Siegall Resignation (Endpoints News, May 2022) —