How to Apply to Mayo Clinic

8 min read Last updated April 20, 2026 9 open positions
Blake Crosley
Blake Crosley Researched using publicly available information, hiring data, and ATS analysis.

Key Takeaways

  • Mayo Clinic is consistently ranked the number one hospital in the United States and employs approximately 76,000 people across campuses in Rochester MN, Phoenix/Scottsdale AZ, and Jacksonville FL.
  • The application portal at jobs.mayoclinic.org is powered by Eightfold AI, which uses machine learning to match candidates to roles. Keyword optimization in your resume is essential for visibility.
  • Mayo Clinic's core value, 'The needs of the patient come first,' is not aspirational; it is the primary lens through which candidates are evaluated at every stage of the hiring process.
  • Interviews are collaborative and values-driven, with behavioral questions focused on teamwork, patient empathy, ethical decision-making, and continuous improvement rather than purely technical assessments.
  • Research experience, publications, and evidence-based thinking are valued across all roles, not just physician and scientist positions. Highlighting intellectual curiosity strengthens any application.
  • The credentialing and background check process for clinical roles is exceptionally thorough. Have all licenses, certifications, NPI numbers, and references prepared well in advance.
  • Mayo Clinic invests heavily in employee development, offering tuition assistance, continuing education, research opportunities, and clear career advancement pathways. Reference these in your application to show you understand their culture.
  • On-site interviews for physician and scientist roles can span multiple days and include presentations, tours, and social events. Prepare thoroughly and treat every interaction as part of the evaluation.
  • Relocation support is available for many positions, and Mayo Clinic actively helps candidates and their families evaluate the community. Rochester, Phoenix, and Jacksonville each offer distinct lifestyle advantages.

About Mayo Clinic

Mayo Clinic is one of the most prestigious and recognized healthcare institutions in the world, consistently ranked as the number one hospital in the United States by U.S. News & World Report. Founded in the 1880s by Dr. William Worrall Mayo and his sons, Dr. William James Mayo and Dr. Charles Horace Mayo, the organization grew from a small family medical practice in Rochester, Minnesota into a global healthcare powerhouse. The Mayo brothers pioneered an integrated, team-based approach to medicine that was revolutionary for its time and remains the foundation of Mayo Clinic's practice model today. Mayo Clinic operates three major campuses: the flagship campus in Rochester, Minnesota, which serves as the headquarters and largest facility; Mayo Clinic in Phoenix and Scottsdale, Arizona, which expanded operations in the Southwest beginning in 1987; and Mayo Clinic in Jacksonville, Florida, which opened in 1986 to serve the Southeast. Together, these campuses employ approximately 76,000 staff members, including over 5,000 physicians and scientists, making Mayo Clinic one of the largest nonprofit healthcare employers in the United States. The organization also operates the Mayo Clinic Health System, a network of community hospitals and clinics across Minnesota, Wisconsin, and Iowa. Mayo Clinic's research enterprise is equally formidable, with over $900 million in annual research spending across more than 3,000 active research studies. The institution houses the Mayo Clinic Alix School of Medicine, the Mayo Clinic Graduate School of Biomedical Sciences, and the Mayo Clinic School of Health Sciences. Mayo Clinic's commitment to education and research means that employees at every level work alongside world-class researchers and clinicians, contributing to medical breakthroughs that shape global healthcare. The organization's primary value statement, 'The needs of the patient come first,' permeates every aspect of operations from clinical care to administrative functions, and is a central theme in how Mayo Clinic evaluates and selects its workforce.

Application Process

  1. 1
    Visit Mayo Clinic's careers portal at jobs

    Visit Mayo Clinic's careers portal at jobs.mayoclinic.org, which is powered by the Eightfold AI platform. Create an account or sign in with your existing credentials to browse open positions across all three campuses (Rochester MN, Phoenix/Scottsdale AZ, Jacksonville FL) and the Mayo Clinic Health System.

  2. 2
    Search and filter positions by location, job category

    Search and filter positions by location, job category (clinical, research, administrative, allied health, nursing, IT, etc.), and employment type. Mayo Clinic posts thousands of positions at any given time. Use keyword searches aligned with your specialty or area of expertise for best results.

  3. 3
    Submit your application through the Eightfold ATS portal, uploading your resu...

    Submit your application through the Eightfold ATS portal, uploading your resume and completing all required fields. The system uses AI-driven matching to assess your fit for the role, so ensure your resume contains relevant keywords from the job description. You may also be asked to complete supplementary questions specific to the role.

  4. 4
    If your application passes initial screening, a Mayo Clinic recruiter will co...

    If your application passes initial screening, a Mayo Clinic recruiter will contact you, typically via email or phone, to discuss the role and your qualifications. For clinical and research positions, this may include a preliminary phone screen to verify licensure, certifications, and experience requirements.

  5. 5
    Qualified candidates advance to formal interviews, which may include a combin...

    Qualified candidates advance to formal interviews, which may include a combination of phone, video (Microsoft Teams), and on-site interviews. Panel interviews with hiring managers, team leads, and potential colleagues are common. For physician and scientist roles, on-site visits often span one to two full days and may include presentations or case discussions.

  6. 6
    Background checks, credential verification, and reference checks are conducte...

    Background checks, credential verification, and reference checks are conducted for all finalists. Clinical roles require verification of medical licenses, board certifications, DEA registration, and malpractice history. Mayo Clinic is thorough in this phase and it may take several weeks.

  7. 7
    Upon successful completion of all checks, you will receive a formal offer letter

    Upon successful completion of all checks, you will receive a formal offer letter. Onboarding at Mayo Clinic is comprehensive, often including orientation sessions that cover the organization's history, values, safety protocols, and IT systems. New hires are paired with mentors or preceptors, especially in clinical roles.

Resume Tips for Mayo Clinic

recommended

Lead with a professional summary that connects your experience to Mayo Clinic...

Lead with a professional summary that connects your experience to Mayo Clinic's mission of putting patients first. Reference team-based care, integrated practice, or multidisciplinary collaboration if these are part of your background.

recommended

Use healthcare-specific keywords that align with the job description

Use healthcare-specific keywords that align with the job description. The Eightfold ATS uses AI matching, so include relevant clinical terminology, procedure names, certifications (RN, APRN, CMA, RHIA, etc.), and technology platforms (Epic, Cerner, etc.) naturally throughout your resume.

recommended

Quantify your accomplishments wherever possible

Quantify your accomplishments wherever possible. Instead of 'managed patient care,' write 'managed care for a panel of 2,400+ patients with 98% satisfaction scores' or 'reduced patient wait times by 22% through workflow redesign.' Mayo Clinic values measurable impact.

recommended

Highlight research contributions, publications, and academic affiliations pro...

Highlight research contributions, publications, and academic affiliations prominently. Mayo Clinic is a research-intensive institution, and even non-research roles benefit from demonstrating intellectual curiosity and evidence-based thinking.

recommended

Include continuing education, professional development, and relevant certific...

Include continuing education, professional development, and relevant certifications in a dedicated section. Mayo Clinic invests heavily in employee development and looks for candidates who demonstrate commitment to lifelong learning.

recommended

For clinical roles, clearly list all active licenses, certifications, and the...

For clinical roles, clearly list all active licenses, certifications, and their expiration dates. Include your NPI number if applicable. Mayo Clinic's credentialing process is rigorous, and having this information readily available accelerates your application.

recommended

Tailor your resume for each specific role rather than submitting a generic do...

Tailor your resume for each specific role rather than submitting a generic document. Mayo Clinic's Eightfold system scores candidates based on fit, so aligning your language with the job posting's requirements and preferred qualifications directly impacts your visibility to recruiters.

recommended

Keep formatting clean and ATS-friendly: use standard section headers (Experie...

Keep formatting clean and ATS-friendly: use standard section headers (Experience, Education, Skills, Certifications), avoid tables, graphics, or complex layouts that may not parse correctly, and save as PDF or Word format as directed by the application portal.

ATS System: Eightfold AI

Mayo Clinic uses Eightfold AI as its applicant tracking and talent intelligence platform. Eightfold uses deep learning and artificial intelligence to match candidates with open positions based on their skills, experience, career trajectory, and potential rather than just keyword matching. The platform powers jobs.mayoclinic.org and handles the full application lifecycle from submission through hiring.

  • Eightfold's AI analyzes your entire career trajectory, not just keywords. Ensure your resume tells a coherent story of professional growth with clear role titles, dates, and responsibilities.
  • The platform extracts skills from your resume automatically. Use standard industry terminology and spell out abbreviations at least once (e.g., 'Electronic Health Records (EHR)') to maximize skill detection.
  • Eightfold considers adjacent skills and career potential. If you are transitioning into healthcare from another field, highlight transferable skills explicitly and connect them to healthcare applications.
  • Upload your resume in PDF or Word format for best parsing results. Avoid headers, footers, text boxes, and multi-column layouts that may confuse the parser.
  • Complete all optional profile fields in the Eightfold portal, including skills, certifications, and education details. The more structured data the system has, the better it can match you to relevant positions.
  • Eightfold may suggest additional positions that match your profile. Review these recommendations, as they may surface roles you had not considered but are well-qualified for.

Complete Eightfold AI Resume Guide →

Interview Culture

Mayo Clinic's interview process reflects the organization's deeply held values of teamwork, integrity, and patient-centered care.

Candidates should expect a structured, thorough, and professional experience that evaluates not just technical competence but cultural alignment with Mayo's mission. The primary value, 'The needs of the patient come first,' is not merely a slogan at Mayo Clinic; it is a lived principle that interviewers actively assess during conversations. Expect behavioral interview questions that probe how you have demonstrated empathy, collaboration, and ethical decision-making in past roles. Questions like 'Tell me about a time you put a patient's needs above your own convenience' or 'Describe a situation where you collaborated with a team to solve a complex problem' are standard. Mayo Clinic uses a collaborative interview model where candidates typically meet with multiple interviewers across different functions. For clinical positions, you may meet with department chairs, division heads, nursing leadership, and administrative partners. This reflects Mayo's integrated practice model where physicians, nurses, administrators, and allied health professionals work as equals in service of patient care. The atmosphere is collegial rather than adversarial; interviewers genuinely want to understand who you are and how you work, not trip you up. For physician and scientist positions, on-site interviews are often extensive, spanning one to two days. These may include grand rounds presentations, research seminars, facility tours, and meals with potential colleagues and their families. Mayo Clinic understands that relocating to Rochester, Phoenix, or Jacksonville is a significant life decision, and they invest heavily in helping candidates experience the campus and community. Dress code for interviews is business professional. Mayo Clinic maintains a conservative, polished institutional culture, and first impressions matter. Candidates should research Mayo's history, recent achievements, and the specific department they are applying to. Demonstrating genuine knowledge of and enthusiasm for Mayo Clinic's mission, research priorities, and patient care philosophy distinguishes top candidates from the rest. Follow-up thank-you notes to each interviewer are expected and appreciated.

What Mayo Clinic Looks For

  • Genuine alignment with Mayo Clinic's core value: 'The needs of the patient come first.' Candidates who can articulate how they have embodied patient-centered care in their careers stand out significantly.
  • Team-oriented mindset and proven ability to collaborate across disciplines. Mayo Clinic's integrated practice model requires professionals who thrive in team environments and respect contributions from all roles.
  • Commitment to excellence and continuous improvement. Mayo Clinic seeks individuals who hold themselves to the highest professional standards and actively pursue ongoing education and skill development.
  • Strong communication skills, both with patients and colleagues. The ability to explain complex medical or technical concepts clearly and compassionately is highly valued across all roles.
  • Integrity, ethical grounding, and accountability. Mayo Clinic's reputation is built on trust, and they hire people who demonstrate honesty, transparency, and a strong moral compass in their professional conduct.
  • Intellectual curiosity and engagement with research or evidence-based practice. Even in non-research roles, Mayo values employees who ask questions, seek data-driven solutions, and contribute to the organization's culture of inquiry.
  • Adaptability and resilience in high-pressure healthcare environments. Mayo Clinic handles some of the most complex cases in the world, and employees must be comfortable with ambiguity, rapid change, and high-stakes decision-making.
  • Cultural sensitivity and commitment to diversity, equity, and inclusion. Mayo Clinic serves patients from every background and actively seeks a workforce that reflects the diversity of the communities it serves.

Frequently Asked Questions

What ATS does Mayo Clinic use for job applications?
Mayo Clinic uses the Eightfold AI platform to power its careers portal at jobs.mayoclinic.org. Eightfold uses artificial intelligence and machine learning to match candidates with open positions based on skills, experience, and qualifications extracted from your resume and application data.
How long does the Mayo Clinic hiring process typically take?
The timeline varies by role, but most candidates report the process taking four to eight weeks from application to offer. Clinical and physician roles may take longer due to extensive credentialing, background checks, and multi-day on-site interviews. Administrative and support roles may move more quickly, sometimes within two to three weeks.
Does Mayo Clinic offer remote or hybrid work options?
Mayo Clinic has expanded remote and hybrid work options for certain roles, particularly in IT, data analytics, finance, and administrative functions. However, clinical, research, and patient-facing roles typically require on-site presence. Each job posting specifies the work arrangement, so review the listing carefully.
What benefits does Mayo Clinic offer employees?
Mayo Clinic offers a comprehensive benefits package including competitive salaries, medical/dental/vision insurance, pension plan, 403(b) retirement savings with employer match, tuition assistance, paid time off, parental leave, wellness programs, employee assistance programs, and access to on-campus fitness centers and childcare at some locations.
Can I apply to multiple positions at Mayo Clinic simultaneously?
Yes, you can apply to multiple positions through the Eightfold portal. However, it is recommended to tailor each application to the specific role rather than submitting identical materials. The AI matching system evaluates fit per position, so customized applications perform better.
What should I wear to a Mayo Clinic interview?
Business professional attire is expected for all Mayo Clinic interviews, whether in-person or virtual. Mayo Clinic maintains a conservative institutional culture, and professional appearance is part of the evaluation. For virtual interviews, ensure a clean, well-lit background and professional dress from the waist up at minimum.
Does Mayo Clinic sponsor work visas for international candidates?
Yes, Mayo Clinic sponsors H-1B, J-1, O-1, and other work visas for qualified international candidates, particularly for physician, scientist, and specialized clinical roles. Visa sponsorship availability varies by position and department, so check the job listing or ask the recruiter during your initial screen.
How important is research experience for non-physician roles at Mayo Clinic?
While not always required, research experience or engagement with evidence-based practice is valued across all roles at Mayo Clinic. The institution's culture of inquiry means that demonstrating intellectual curiosity, familiarity with research methodologies, or experience supporting clinical trials can distinguish your application even for administrative or technical positions.
What is Mayo Clinic's approach to diversity and inclusion in hiring?
Mayo Clinic has a dedicated Office for Equity, Inclusion, and Diversity and actively recruits from diverse candidate pools. The organization has employee resource groups, diversity scholarships, and inclusive hiring practices. They track and report workforce diversity metrics and have committed to increasing representation across all levels of the organization.
How can I follow up on my application status at Mayo Clinic?
You can check your application status by logging into your account on the Eightfold careers portal at jobs.mayoclinic.org. If you have been in contact with a recruiter, you may also follow up via email. Mayo Clinic receives a high volume of applications, so allow at least two weeks before following up on a new submission.

Open Positions

Mayo Clinic currently has 9 open positions.

Check Your Resume Before Applying → View 9 open positions at Mayo Clinic

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