Real-World Evidence Medical Lead

At Roche you can show up as yourself, embraced for the unique qualities you bring. Our culture encourages personal expression, open dialogue, and genuine connections,  where you are valued, accepted and respected for who you are, allowing you to thrive both personally and professionally. This is how we aim to prevent, stop and cure diseases and ensure everyone has access to healthcare today and for generations to come. Join Roche, where every voice matters.

The Position

At Roche, we harness the power of science and data to transform healthcare and improve patient outcomes. As an RWE Medical Lead, you will play a key role in shaping and delivering evidence generation strategies by leading the execution of Real World Evidence (RWE) activities, non-interventional studies and Medical Affairs programs across therapeutic areas.

In this role, you will be responsible for the end-to-end planning, execution and oversight of both local and global RWE studies, ensuring all operational aspects are delivered efficiently and in compliance with the highest quality standards, including ICH/GCP and GVP/GPP guidelines. You will transform data into meaningful insights that inform publications, regulatory submissions, internal decision-making, and healthcare system improvements.

You will work in close collaboration with global and local cross-functional teams including Clinical Operations, Disease Area teams, investigators, CROs and external partners to ensure successful delivery of evidence generation projects. You will also contribute to driving innovation by leveraging new data sources, digital tools, AI and scalable analytical approaches.

This role reports directly to the Evidence Generation Strategy Lead.

Key Responsibilities 

• Lead the end-to-end planning, execution, and oversight of local and global RWE studies, including non-interventional studies, registries, epidemiology and Phase IV studies

• Build and lead cross-functional study teams, ensuring clear roles, responsibilities and delivery of study objectives

• Act as a key cross-functional partner, driving strong internal and external communication, alignment and collaboration across Medical, Clinical Operations, Disease Area teams, investigators and external stakeholders

• Ensure study compliance with ICH-GCP, GVP, GPP, local regulations and Roche quality standards, maintaining continuous inspection readiness

• Provide scientific and operational input into study design, protocol development, feasibility assessments and study documentation

• Drive operational excellence by implementing and maintaining key study systems, including site selection, monitoring plans, vendor oversight and risk-based quality management approaches

• Lead Study Management Team meetings and ensure effective governance and stakeholder alignment

• Oversee CROs and external vendors, including selection, contract negotiation, onboarding and performance management

• Manage study budgets, including planning, tracking, forecasting and variance management

• Ensure high-quality study execution across all phases, including start-up, conduct and close-out activities

• Support continuous improvement of processes and contribute to SOP development and updates

Who You Are

• Degree in Medicine or Pharmacy is preferred or Life Sciences–related field; a PhD in Epidemiology, Biostatistics or a data-related discipline is highly desirable

• At least 5 years experiences in pharmaceutical industry within Medical Affairs, RWE, or Clinical Operations 

• Hands-on experience in Real World Evidence (RWE) and/or data generation projects is highly desirable

• Fluency in Turkish and English

• Strong understanding of Real-World Evidence strategies, observational study designs and data privacy regulations

• Strategic mindset with a proactive approach and the ability to anticipate challenges and drive solutions

• Excellent communication and problem-solving skills with the ability to engage and align diverse stakeholders

• Experience working with cross-functional and global teams in a matrix environment

• Demonstrated leadership in managing complex study teams and driving project execution

• Solid knowledge of ICH-GCP, GVP, GPP, and applicable regulatory frameworks

• Agile mindset with the ability to work in a dynamic and evolving environment

Who we are

A healthier future drives us to innovate. Together, more than 100’000 employees across the globe are dedicated to advance science, ensuring everyone has access to healthcare today and for generations to come. Our efforts result in more than 26 million people treated with our medicines and over 30 billion tests conducted using our Diagnostics products. We empower each other to explore new possibilities, foster creativity, and keep our ambitions high, so we can deliver life-changing healthcare solutions that make a global impact.

Let’s build a healthier future, together.

Roche is an Equal Opportunity Employer.