Executive Director, Head of Clinical Data AnalyticsSouth San Francisco, California, United States, Princeton, New Jersey, United States
Executive Director, Head of Clinical Data Analytics
About Us
Reports To: VP, Biometrics
Location: Princeton, NJ – On-site 4 days per week (Mon to Thurs)
Position Summary
The Head of Clinical Data Analytics is a strategic leader responsible for the architectural vision and operational execution of data delivery and advanced insights at Kardigan. This role reports to the head of Biometrics and unites Statistical Programming and Data Science into a single, cohesive engine. You will build, lead, and develop a high-performing team, and lead the modernization of our Stats Programming & Data Science infrastructure—bridging traditional SAS-based regulatory production with R-based data science—to create real-time, automated dashboards that accelerate decision-making across our cardiovascular pipeline.
The Head of Clinical Data Analytics serves as a thought-leader in advanced analytics, ensuring high-quality, compliant data deliverables while enabling predictive insights, automation, and scalable analytics platforms.
This position will also be responsible for departmental & organizational strategic initiatives.
Essential Duties and Responsibilities
- Develop the Data Analytics function and strategy aligned with the organizations clinical development goals. Lead the recruitment, on-boarding, and management of staff and external vendors and consultants
- Ensure data interpretation and statistical analysis support high-integrity decision making and regulatory submissions
- Partner closely with Biostatistics, Medical, Clinical Operations, Safety, and Regulatory to ensure insights inform decision making and strategy
- Modernization Roadmap: Define and execute the strategy to transition from legacy programming silos to a modern, hybrid R/SAS environment.
- Platform Ownership: Lead the design and deployment of an internal analytics platform (e.g., R-Shiny, Spotfire) to provide cross-functional teams (Clinical, Safety, Operations) with real-time, self-service data review capabilities.
- Regulatory Quality: Oversee the internal team or CRO delivering SDTM, ADaM, and TFLs for regulatory submissions (IND, NDA/MAA).
- Submission Strategy: Develop strategies for electronic submission packages, ensuring "inspection-readiness" is built into the data pipeline.
- Partner with Biostatistics to ensure alignment between analysis plans, programming execution, and advanced analytics approaches.
- Process Engineering: Drive "Lean Programming" by leveraging automation to reduce turnaround times to support data monitoring activities.
- Standardization: Develop a library of reusable R-packages and SAS macros to ensure reproducibility and consistency across all clinical programs.
- Establish best practices, SOPs, and governance frameworks for analysis across programs
- Ability to assess and transform capabilities through AI and Automation solutions or strategies
- Up to 20-30% domestic and international travel may be required
Qualifications and Preferred Skills
- M.S. in Biostatistics, Data Science, Computer Science, or a related quantitative field is required.
- PhD preferred.
- 12+ years in Biometrics/Clinical Analytics, with at least 5 years in a leadership role within a biotech or pharma environment. Or 10+ yrs with a PhD
- Cardiovascular Domain Expertise: Deep understanding of the unique data challenges in CV trials (e.g., longitudinal endpoints, high-frequency monitoring data).
- Strong knowledge and hands-on technical expertise of SQL, Python/R, and visualization tools
- Prior experience working in small fast-paced company highly preferred.
- Extensive experience in drug development and working with regulatory agencies such as FDA and EMA for submissions.
- Hands-on exposure to modern analytics platforms, cloud environments, and AI/ML enablement in clinical development
- Experience working in an environment where knowledge of and adherence to SOPs and regulatory guidelines are required
- Excellent collaborator, communicator (verbal & written), and influencer across technical and non-technical audiences
- Detail and process oriented and demonstration of strong project management skills.
- Demonstrated success in building & leading high-performing teams and driving change in a corporate environment
Exact Compensation may vary based on skills, experience and location.
Pay range
$260,000 - $338,000 USD
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